Foam sclerotherapy - FDA approved drugs
Sclerotherapy works well around the ankles and sometimes requires more than one treatment, especially if you have a densely populated spider and reticular veins around the ankle called corona phlebectasia ('crowning of the ankle with veins'). Polidochanol is a great agent for this. See the link below from the Doctors TV Show.
There are two recently FDA approved sclerosing agents now available in the US. Asclera is polidocanol and Fibrovein is sodium tetradecyl sulphate. Both of these can be used as a foam.