Why my face is changing it shape? (photos)

July this year i noticed that my facial shape is changing leading to a not so soft aura, i noticed that the left part of my face sunking near the masseter area whenever im applying some cream, that i really never felt before. Im a transgender whos undergoing a hormonal replacement therapy and before it actually happened im on high dose of estrogen. Im afraid im suffering from a serious condition and its quite depressing since its targetting my face , please give me some advices thank you so much

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