Perlane Vs Radiesse for Cheeks

What are the pros and cons of Perlane and Radiesse for cheeks? Is it true that Perlane will not cause lumps, will not migrate, and is smoother and better for women?

Doctor Answers 13

Perlane vs Radiesse

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I would consult with a reputable, well-trained and experienced provider for a full assessment and education on both of these dermal fillers. They are both great for cheek volume replacement but have distinctive characteristics that should be explained fully before injection.

Seattle Facial Plastic Surgeon
4.7 out of 5 stars 231 reviews

Perlane vs Radiesse

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How to choose between the two?  I prefer Perlane just because to me it is a more natural product found in soft tissues.  Radiesse is a calcium based product not much different than what is found in bone.  It can give a nice result as well, but you can not dissolve it if you have a problem with it.

Steven Wallach, MD
New York Plastic Surgeon
4.2 out of 5 stars 30 reviews

Perlane vs Radiesse for the cheeks? Great question!

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Both Perlane and Radiesse are great choices for cheek augmentation.  They are thicker than Restylane and provide a nice, "umph" for 6-9 months.  For my first time cheek patients I often choose Perlane because it is, "kinder and gentler" the first few days.  The Radiesse tends to have more swelling during this time.  The advantage of the Radiesse is that it lasts maybe a couple of months longer than the Perlane.  I will often give patients this option after they've seen the wonder of great cheeks and are willing to undergo 3 days of swelling for more months of cheeks.

In summary, they are both great, the Radiesse causes a little more initial swelling but lasts a little longer.

David C. Mabrie, MD
Bay Area Facial Plastic Surgeon
4.7 out of 5 stars 159 reviews

Fillers for the cheeks

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There are a variety of different fillers for the face and each has its own specific characteristic and longevity. The most important thing is the quality of your injector. An experienced injector should be able to give you smooth, natural results, no matter what material is used.

Specifically for the cheeks, I prefer to use Radiesse. I use an intra-oral technique where the filler is injected through the mouth. I have been using this method for over a year and will never go back to puncturing through the skin! I find that there is minimal bruising and swelling - and any that occurs is on the inside of the mouth and is not noticeable to anyone else. The results last about 12 months. I have used Perlane in this manner but find that it does not last as long and required more vials to get the same results.

I would go with Perlane

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Either product can give you lumps depending on the experience of the injector.  The beauty of hyaluronic acid based fillers like Perlane, Juvederm, Voluma, or Restalyne is that they are reversible.  So I prefer Perlane because I can assure my patients who have never had filler before, that they are not "stuck" if they don't like it... that gets them over the fear and onto the benefits of filler.

Sheila S. Nazarian, MD
Beverly Hills Plastic Surgeon
4.8 out of 5 stars 56 reviews

Perlane vs Radiesse

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I really like both products for the cheeks and cheek lifts.  Radiesse provides up to a year of volume versus up to 15 months with Perlane as long as you get the 4 month touch up recommended by the companies.  Perlane is better if you have thin skin and I feel Radiesse does a better job with heavier cheeks and thicker skin.  

Mike Majmundar, MD
Atlanta Facial Plastic Surgeon
4.5 out of 5 stars 50 reviews

Combining Ulthera with facial fillers and Radiesse - Santa Monica

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Radiesse is an excellent option. I combine the Radiesse with Ulthera to lift up the cheek and submalar areas of the face. Raffy Karamanoukian Los Angeles

Raffy Karamanoukian, MD, FACS
Los Angeles Plastic Surgeon
4.8 out of 5 stars 95 reviews

Perlane Vs Radiesse for Cheeks

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Both products can be excellent for cheek augmentation. The more key decision is to choose an experienced and expert injector. The injector can then guide you on which product he/she prefers to use for your case.

Kris M. Reddy, MD, FACS
West Palm Beach Plastic Surgeon
4.5 out of 5 stars 56 reviews

Perlane vs Radiesse

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Greetings Joann~

Perlane and Radiesse are both excellent products and work beautifully in the cheeks.  I definitely do NOT agree that Perlane is inherently smoother and won't cause lumps...these things are very injector dependent and not substance dependent.  Good injectors can get beautiful smooth results in men and women with either product. Some patients do feel they get more longevity with Radiesse than Perlane for the cheeks.  If you are apprehensive about having fillers done in the cheeks, then perhaps Perlane is a good choice for the first time since it can be easily dissolved if you don't like the results.  Your most important choice may not be so much with product as it is with injector....choose your injector wisely and it will make all the difference.

Good luck~

Dr. Grant Stevens

Grant Stevens, MD
Los Angeles Plastic Surgeon
4.7 out of 5 stars 152 reviews

Clear pros and cons of Perlane vs. Radiesse for cheeks.

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Radiesse tends to be more expensive, and it definitely lasts longer, which means, if you love your results you are thrilled, and if you don't like them, you are very unhappy. Unlike Perlane, Restylane, and Juvederm, Radiesse can't be easily removed with hyaluronidase if you are displeased or if there is a reaction.

I disagree with the concept that "Perlane is softer and looks better for WOMEN". That is a strange suggestion. Filler is sculpting material and the right skilled, trained, experienced, conscientious and artistic dermatologist or plastic surgeon should make lovely results with either. Overuse of either will give bad looking results.


Jessica J. Krant, MD, MPH
New York Dermatologic Surgeon
4.7 out of 5 stars 41 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.