The main differences between filler types are consistency and longevity. While some fillers are definitely better placed deep into the skin because of their thickness like Radiesse, which is not generally used in the lips for this reason, often doctors have personal choices in the fillers they like to use in different places. In our practice, we use primarily hyaluronic acids, a gel like substance, whereas Radiesse (calciumhydroxylapatite) has a consistency of paste.
Often we use the hyaluronic acids for a patients' first treatment simply because they are softer and gentler. For patients who want a longer-lasting filler and want more "umph," we use Radiesse because it lasts longer. However, it tends to swell more and you may have a tad more bruising.
Another difference between hyaluronic acids and calciumhydroxylapatite is that hyaluronic acid may be reversed with an injection of Wydase, while calciumhydroxylapatite may not.