You should alternate the .04% and the .1% nightly for the first week to slowly get used to the higher strength. Your acne should not flare and you should not have increased irritation if you introduce the .1% slowly. Skip nights if you become too dry and use an oil-free moisturizer.
Will my Acne Get Worse if I Change from Retin a Micro 0.04% to the 0.1%?
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These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.