Do the results of Sculptra depend on proper preparation, such as dilution and advanced preparation?

Over a period of 2 1/2 years I had Sculptra injected in my temples and cheeks 20-22 times. Each time a total of 10 cc was used between the temples and cheeks. I did not notice any improvement. Is this normal? and is it possible the Sculptra was not prepared properly (diluted too much and/or not prepared far enough in advance )?

Doctor Answers 3

No response to Sculptra

There is a rare patient who does not respond well to Sculptra. It seems as though if this happens, it is more likely to be an older patient, say in the late 70's or older. Even these patients can respond if treated again, however.

Your experience is very curious, and I would encourage you to ask your doctor to discuss it with the manufacturer of Sculptra.

New York Dermatologist
5.0 out of 5 stars 8 reviews


If the 10 cc were in one bottle of Sculptra, the dilution was appropriate.  On average, 1 bottle of Sculptra is required for each decade of life.  For example, if you are 60 years old, you may require 6 bottles of Sculptra injected over a few months and the results should last 1 to 2 years.  Speak to your physician to discuss why you are not having the desired effect.  If you are still concerned, seek a second opinion.  You may require a different treatment to achieve the results you would like.

Martie Gidon, MD, FRCPC
Toronto Dermatologist
5.0 out of 5 stars 22 reviews

Sculptra and dilution

The standard dilution is 9 or 10cc for one vial of Sculptra.  I have no idea why you would need 20 injections over the course of a 2 1/2 year period.  Please get a second opinion by a board certified dermatologist with a great deal of experience in cosmetics.

Michele S. Green, MD
New York Dermatologist
5.0 out of 5 stars 76 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.