What is the difference between vitrase and hyaluronidase 1500iu in their ability to dissolve filler without adverse effects?
Doctor Answers 1
Hyaluronidase, Wydase, Vitrase, Hylenex
Vitrase is a brand of hyaluronidase, just as Wydase is. Generic hyaluronidase is commonly used and would only carry the name hyaluronidase. These are all made with bovine (cow) derived hyaluronidase. Because of that, there is a small risk of the patient being allergic. Hylenex is made from hamsters genetically modified to produce human hyaluronidase and therefore carries a lower risk of allergy. Because it comes from a hamster, it still can cause an allergy in some patients, but it is a lower risk. The overall risk of allergy is still small regardless of which product you use. All of the products will do a fine job of dissolving hyaluronic acid (Juvederm/Restylane/others)
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