Deep folds require more filler...
It is not that fillers like Juvederm, Perlane, and Radiesse will not help deep nasolabial folds, it is just that it requires more filler to the fold as well as the cheeks to lift the area. It therefore may not be "cost-effective". Fine lines are fine with Juvederm or Restylane, but lasers like the Deep FX will give more permanent improvement. One thing I think: avoid silicone. Over the years, it results in a muzzled, "monkey" look to the mouth area that gets worse, not better over 10-20 years. Silicone never goes away and expands over time.
Fillers can help with the deep lines and wrinkles around the mouth, however the results are temporary. You may want to consider laser treatments for the fine wrinkles.
I suggest you try Belotero for those deep lines. I have found that this product is great at achieving a natural looking improvement.
Is Juvederm Effective for Deep Nasolabial Lines?
There are several formulations of Juvederm, some of which are better suited to deeper areas of volume loss of filling deeper folds or lines. Radiesse can be used as well for these purposes. There are other options as well, and a lot of this depends upon surgeon preference. Kenneth Hughes, MD Los Angeles, CA
Using Juvederm for Deep Nasolabial Folds
I have successfully used Juvederm Ultra & Ultra Plus, Restylane, Perlane, Radiesse and Artesense for deep nasolabial folds/lines. Most importantly, you want an expert injector (e.g. dermatologist) who understands your skin and how much and which filler to inject, and at what depth, and in combination with what other treatments. Dr. Benjamin Barankin, Toronto Dermatology Centre.
Deep and fine lines with Juvederm
Juvederm will work very well for the deep nasofacial lines.The improvement will last 6 to 8 mopnths, possibly longer.
Radiesse (Calcium Hydroxyappatite) can last longer: 10to 12 months or possibly longer.
For fine wrinkles on the upper lip, a few units of Botox followed in 1 week by Traditional Laser Resurfacing would be the best treatment. Unfortunately, there is a long period of downtime (7-9 days or longer). Alternately, Botox followed by Fractional Laser Resurfacing (2-4 sesions 4-6 weeks apart) can be quite effective.
Make sure you are treated by an experienced, Board CertifiedDermatologist or Plastic Surgeon.
Radiesse, Beverly Hills Radiesse, Los Angeles Radiesse, Juvederm
Yikes, I'm not a fan of injecting free silicone into the face or body because of the very real risk of serious complications. You can do a quick search on the web to see the reported silicone complications. For deep smile lines also called nasolabial folds you may consider:
Juvederm Ultra Plus
All of these are thicker fillers than Juvederm and should give greater filling effects to the folds. For the fine smile lines, around the mouth, we use either Botox or Dysport with really nice results. I'm not sure how a Laser would help fill in the nasolabial folds as these are meant to re-surface the skin, not fill in folds.
Juvederm or Perlane is great for the nasolabial folds. It helps reduce the deep depression. It is not good for fine lines.
Radiesse ,Perlane and Juvederm Ultraplus are better choices for deep nasolabial folds
When we are treating deep nasolabial folds robust fillers such as Radiesse, Perlaneor Juvederm Ultra plus work much better than Juvederm and Resylane
They will add volume as well as filling the folds.
For very deep folds we add Juvederm or Restylane on top in a layered fashion for better outcome
Fillers are great for deep folds
Juvederm is very effective for the nasolabial lines. You may also want to inquire about Radiesse, this works great for very deep folds; and Radiesse lasts between 12 to 18 months.