Possible Granuloma.

I've asked on the board before. I got restylane under the eye more than 3 years ago, and it created a large fat and hard lump, that has persisted for the past 3 years. I think it is scar tissue under my eye now (granuloma). If this a 'granuloma', then what can be done? Can hyaluronidase help against 'granuloma'?

Doctor Answers 4

Granuloma after Restylane

It is unusual for a granuloma to form in this area.  It is likely product. It is possible to inject a small amount of Vitrase into the area to see if it brings down the bump.  It will work beautifully if is product.  I advise you seek an exam with an experienced injector to determine if this is an option. 

Los Angeles Facial Plastic Surgeon
4.4 out of 5 stars 7 reviews

If the bump is due to Restylane it could be treated with hyaluronidase.

Scars or granulomas following Restylane would be extremely unlikely.  I have probably performed 20,000 injections with Restylane over the past 10 years and I have never seen it.  If there is any residual Restylane in the bump, I would recommend treating it with Hyauronidase to see if it will go away.  That is a very safe treatment option.

Mark Taylor, MD
Salt Lake City Dermatologic Surgeon
4.2 out of 5 stars 18 reviews

Lower lid bump

You need a proper examination to first find out what the lump is and then consider treatment options. Consult an oculoplastic surgeon.  There are surgical and nonsurgical options.

Mehryar (Ray) Taban, MD, FACS
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 74 reviews

It is unlikely to be a granuloma.

Restylane is very unreactive. This means that it stimulates very little inflammation.  Scar tissue and granuloma are unlikely.  The lump is likely high in the dermis and has resisted removal by natural means.   I have seen product persist in this fashion for over three years.  The appropriate treatment to remove this is in fact an injection of the enzyme hyaluronidase.  This will remove the lump most likely

Kenneth D. Steinsapir, MD
Beverly Hills Oculoplastic Surgeon
4.9 out of 5 stars 26 reviews

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