Does Botox for Hyperhidrosis Work?

Can someone get Botox for hyperhidrosis (i.e. Botox for excessive sweating)? Is this experimental or is it FDA-approved? Does it work?

Doctor Answers 50

Sweating - Botox is a safe treatment

Excessive sweating makes many a people self-conscious. A single Botox treatment can give back self-confidence for aprox. 5 - 10 months.  

Mainz Dermatologic Surgeon

Botox for Hyperhidrosis

Botox for hyperhidrosis works very nicely and successfully. It is most ideal for hyperhidrosis of the underarms, less desirable and more painful for hyperhidrosis of the hands and feet. For obvious reasons, people are reluctant to have Botox injected into the palms and soles of the feet - which are sensitive areas of the body. Regardless of the area injected, it has an immediate effect and lasts for as long as 6 months.

Hratch Karamanoukian, MD, FACS
Buffalo Phlebologist
4.8 out of 5 stars 41 reviews

Botox Works for Hyperhidrosis

If you suffer from hyperhidrosis, otherwise known as excessive sweating, we can inject Botox to control it. In this application, Botox works by temporarily blocking chemical signals from the nerves that stimulate sweat glands. It is FDA approved for use under the arms and also works well for sweaty areas on ALL other parts of the body including the hands, feet and groin. Results can last for up to four to nine months. Please be sure to consult a board-certified dermatologist who has experience treating hyperhidrosis with Botox.

Mitchel P. Goldman, MD
San Diego Dermatologic Surgeon
4.9 out of 5 stars 25 reviews

Botox for hyperhydrosis

Thank you for your question.  Botox is a very effective treatment for hyperhidrosis (armpit, hands, feet, scalp/face, etc).  The dosing is typically based on areas treated but can vary around 50 - 100 units per side depending on how large the treatment area.  Duration also depends on dose, but can vary from 3-6 months.  For the armpit region, you may also want to consider miraDry as it provides a longer lasting relief.

Young R. Cho, MD, PhD
Houston Plastic Surgeon
4.8 out of 5 stars 37 reviews

Hyperhidrosis - Treatment in Montreal

The use of Botox to control hyperhidrosis is FDA approved and can be very effective when administered by an experienced physician. Injected near the sweat glands, Botox can reduce excessive sweating in palms, feet and underarms up to 80% and usually lasts an average of 7 months. In some cases the results can even last up to a year.

Often patients feel that excessive sweating has affected their day to day life and causes a great deal of self-consciousness. A Botox treatment has really helped my patients who experience excessive sweating regain their confidence.

Steven Bernstein, MD
Montreal Dermatologic Surgeon
5.0 out of 5 stars 7 reviews

Botox for Hyperhidrosis

In experienced hands Botox has had a long, safe history of use—and has been approved for use in over 75 countries. Botox was FDA approved in 2002. Botox has been a great treatment to help with Hyperhidrosis with many of my patients. The result will usually last about three to four months at which point the sweat begins to reappear.

Dennis Gross, MD
New York Dermatologist
4.4 out of 5 stars 5 reviews


BOTOX interferes with the transmission of signals that are sent to your glands and muscles. This is how it reduces excessive sweating. Treatment of hyperhidrosis with Botox is FDA approved and it is not in an "experiential" phase.

Jerome Edelstein, MD
Toronto Plastic Surgeon
5.0 out of 5 stars 176 reviews

Botox for Hyperhydrosis

Hyperhydrosis is a condition that involves excessive sweating, which is sometimes accompanied by bad odor and unsightly dampness.  Usually, underarm sweating is effectively managed with topical, over the counter antiperspirants.  When this does not effectively treat perspiration, from Hyperhidrosis, Botox may provide relief. 

Botox is an FDA approved treatment for Hyperhydrosis that helps control excessive sweating by temporarily blocking chemical signals from the nerves that stimulate sweat glands.  When the sweat glands do not receive chemical signals to sweat - the amount of perspiration is reduced.  Self-confidence is increased when excessive sweating is finally under control. 

100 units of Botox Cosmetic is injected through a very small needle, into the skin of each underarm.  The treatment will hinder the nerve endings of the motor endplates.  The Botox injections will not only cease the excessive sweating, but it will also provide a simultaneous disappearance of the odor associated with the excessive perspiration. 

The results from Botox are not permanent, however.  Results will start to appear during the first few weeks after treatment.  You will be able to enjoy up to 8 months (or longer) of dryness, and reduced odor.  After this time period, a repeat Botox Cosmetic treatment will be necessary.


Narin (Joe) Apisarnthanarax, MD
Houston Dermatologist
4.5 out of 5 stars 13 reviews

Botox works very well for under arm excess perspiration

Botox is the gold standard to treat excess sweating (hyperhidrosis) under the arms.  An oral medication (Robinul) can be used in conjunction with Certain-Dri with good effect.  Iontophoresis can also be helpful, but under the arms, Botox works best.

Charles E. Crutchfield III, MD
Minneapolis Dermatologic Surgeon
4.3 out of 5 stars 15 reviews

Botox for Hyperhidrosis

Botox is an FDA approved drug for treatment of excess sweating in areas like the underarms, hands and feet.  The efficacy of the treatment varies so patient selection is key.

Kris M. Reddy, MD, FACS
West Palm Beach Plastic Surgeon
4.4 out of 5 stars 41 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.