What is the Difference Between Fillers?

Doctor Answers 5

What is the difference between fillers?

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There are many fillers on the market in the United States. FDA approval should not alone make the physician or patient feel comfortable with using one. It is very important for both doctor and patient to understand how fillers interact with the body. Some fillers such as silicone and poly methymethacralate have been shown to be surrounded by mutinucleated giant cells. These cells may be dormant for 1-2 years and then be triggered , and then begin to reject the material. Patients may experience redness and swelling.

Patients may be drawn to these fillers because of their permanence. I prefer the hyaluronic acid fillers, they are natural to our bodies, relatively long lasting-12-18 months, and reversible.

Atlanta Facial Plastic Surgeon
4.6 out of 5 stars 33 reviews

Fillers in USA are Safe and Long Lasting

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There are significant differences between the facial fillers now available in the United States.  Improved Safety and Longevity are the good news.   It is important to have a Dermatologist, Facial Plastic Surgeon or Plastic Surgeon assess your needs to help make an informed decision.  For more info--go to Dove Press and search for Fillers for peer reviewed information or visit AAFPRS.org web site.

James Newman, MD, FACS
Palo Alto Facial Plastic Surgeon
4.1 out of 5 stars 11 reviews

The difference between fillers is a broad question to answer

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In the US, we have several groups of fillers available and FDA-approved.  In other countries, of course, there will be different fillers available as well.

We have a group we refer to as "HA fillers" (hyaluronic acid fillers).  These last about 12 months, depending upon where they are used in the face.  They include Restylane, Perlane, and Juvederm, as examples.

The "collagen stimulators" include Sculptra and Radiesse.  These fillers last longer than HA fillers.  Radiesse may last as long as 18-24 months, while Sculptra lasts 2-5 years. 

Various fillers may be used together, in different parts of the face, for best results in some people.  Your plastic surgeon or dermatologist should be able to guide you.

Carmen Kavali, MD
Atlanta Plastic Surgeon
4.6 out of 5 stars 46 reviews

Fillers 101

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Hey 234680anon – this is a great question! I am often asked in my
practice about the differences between dermal fillers and where is the best place to use each one. 

Restylane is a Hyaluronic Acid (HA) that has a consistency of jelly. It’s my go-to dermal filler for the under-eye area (tear trough), nose (non-surgical rhinoplasty), and sometimes for the chin and cheek. Because it is an HA filler, Restylane is reversible with an injected enzyme (hyaluronidase) allowing for correction and control with results.

Radiesse is thicker than Restylane and is comprised of Calcium Hydroxlapatite (CaHa) with a consistency of peanut butter. It is an opaque dermal filler that I sometimes use for the cheek and chin. Radiesse is non-reversible and can last upwards to 1 year.

The latest dermal filler is Juvederm Voluma. It is an HA and translucent like Restylane, with a consistency of tofu or marshmallow. Because Juvederm Voluma produces a rounded-effect it’s ideal for cheek lift and chin (non-surgical chin augmentation). My patients and I have been really excited about the results. As an HA dermal filler, Juvederm Voluma is also completely reversible with a longevity of up to 2 years.

The best place to determine which dermal fillers is right for your unique goals is to meet with an experienced physician to review your treatment options.

David C. Mabrie, MD
Bay Area Facial Plastic Surgeon
4.8 out of 5 stars 141 reviews

Filler differences

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There are many different types of fillers around, with Radiesse being one of them.  Radiesse is made of a naturally occuring substance found in bone, called calcium hydroxylapatite.  One of the benefits of Radiesse is that it gives more lift and lasts longer than most hyaluronic acid-based fillers such as Juvederm, Perlane and Restylane with results lasting up to a year or more.  You and your doctor can decide during an in-person evaluation which filler treatment is right for you. 

Joshua L. Fox, MD
Long Island Dermatologic Surgeon
5.0 out of 5 stars 22 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.