Is it possible for hyaluronidase to not work? (Photo)

Question

Had juvederm injected to marionette lines roughly a month ago. One week after, was unhappy, so recieved a laser treatment to "re-mold" the filler. Received the same laser treatment a week later. Still wasn't happy, went in for hyaluronidaise on both injection sites. A week later, juvederm area looked even more raised, and felt hard. Recieved another round of hyaluronidaise yesterday- everything looks worse. Advice?

Jason Emer, MD · Answer

Hyaluronidase will reverse Juvederm, but it can take a series of treatments. Keep in mind, you may also have some swelling from your hyaluronidase injections, which can last 1-2 weeks. See an expert. Best, Dr. Emer

Maria Milone, MBBS · Answer

Thankyou for your question .From the photo it appears you have redness and swelling around the nasoabial lines( ie end of line starting from the nose and heading towards the mouth) rather than the marionette (which is the line from the corner of the mouth to the jawline) .Regardless of where it is , you may be experiencing an inflammatory reaction to the filler or  an infection , In this case you may need steroid (oral or injected but need to be cautious with injected steroid due to risk of causing skin/soft tissue depression )or  antibiotic treatment especially if you are going to have hyaluronidase again . Your physician should be able to make this assessment and treat accordingly. Best of luck.

Faiyaaz Kalimullah, MD, FAAD · Answer

Thank you for your question.  I'm sorry to hear that you aren't pleased with the results of your Juvederm treatment.  Juvederm is a hyaluronic acid filler, and should respond to hyaluronidase injections.  That said, it may take multiple sessions to fully reverse the effects of your Juvederm, and the effectiveness of each session can depend on the amount and concentration of hyaluronidase being used.  I would recommend following-up with your injector to discuss your concerns.  It may also be worthwhile to get a second opinion from an experienced cosmetic dermatologist or plastic surgeon.  Best of luck!

Is it possible for hyaluronidase to not work? (Photo)

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Is it possible for hyaluronidase to not work? (Photo)

Answers (3)

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Everything you need to know about Hyaluronidase

Our mission is to create a world where every investment in modern beauty is Worth It.