Taking short breaks from isotretinoin (Accutane) is sometimes needed when there are side effects or lab abnormalities. In certain instances, once the issue is resolved, then it is OK to re-start the medication. In other instances, there is too much of a risk that the problem will recur, and the medication is discontinued permanently. It sounds that in your case, the white count fell and your doctor monitored you until it became normal again. Once the medicine is restarted you will continue to reap its benefits and your skin will continue to improve. Your doctor will keep a close eye again on the white count. Do not worry that you had this interruption, patients take breaks from isotretinoin all the time and resume again. Be well!