How great is the incidence of botulism post-Botox? Also, I'm Asian & am concerned about heightened sensitivity to drugs, etc.

...does a sensitivity to meds in general predispose a person to sensitivity to Botox? I For example, I cannot tolerate narcotic pain meds at all. In the past, when I've gone to the doc for what I felt was a full-blown illness or infection, I've been told that most people wouldn't have even noticed the symptoms I had. Should I be extra careful when considering Botox and fillers and should I take any extra precautions if I decide to proceed with them? Am I at greater risk for complications?

Doctor Answers 8

Getting botulism from cosmetic botox - doesn't happen!

Botox has been around for over 20 years and with proper cosmetic usage by trained professionals such as a dermatologist, there is zero risk of developing botulism. Asians are no more sensitive to botox/fillers than anybody else, and sensitivity or allergy to these products is incredibly rare.

Toronto Dermatologic Surgeon
4.8 out of 5 stars 50 reviews

Botulism from Botox?

With dose used in cosmetic injections, you can't get botulism from authentic Botox. There is not enough units. This should not be a concern. If it is, try doing just one area and see how you tolerate things.

Steven F. Weiner, MD
Panama City Facial Plastic Surgeon
4.7 out of 5 stars 41 reviews

Botox and general sensitivity

You really need not worry since Botox is injected into the muscle where it is utilized and metabolized locally. the incidence of any side effect of Botox is extremely low and botulism is not a real concern despite the FDA

Melvin Elson, MD
Nashville Dermatologist
5.0 out of 5 stars 4 reviews

Botox and Sensitivity

If you are concerned that you have a sensitivity to medications you should try just one area of Botox first to see if you have any reactions that don't seem typical.  Please consult an expert.  Best, Dr. Green

Michele S. Green, MD
New York Dermatologist
5.0 out of 5 stars 74 reviews

How great is the incidence of botulism post- Botox? Also, I'm Asian & am concerned about heightened sensitivity to drugs, etc.

Thank you for your question. You will not be exposed to botulism with Botox treatments.You are not at any greater risk with Botox or filler injections. 


Martin Jugenburg, MD
Toronto Plastic Surgeon
4.9 out of 5 stars 458 reviews

Incidence of botulism post-Botox? Also, I'm Asian & am concerned about heightened sensitivity

  Hi, I have used Botox or one of the other neurotoxins (Xeomon, Dysport) for over 30 years.  Millions of Botox treatments have been performed using Botox and with authentic product, there is a zero chance of getting botulism.  The cases reported of patients getting botulism are associated with bootleg Botox, not the real Botox from Allergan.  Asians are no more sensitive to Botox than anyone else.  Be sure to see an MD that is an experienced Botox provider and beware of a cheap price that's "too good to be true".

Hope this helps.

Francis R. Palmer, III, MD
Beverly Hills Facial Plastic Surgeon
4.6 out of 5 stars 24 reviews

Botulism and Botox Cosmetic

Thank you for your question.

The concentration of the purified form of Botox Cosmetic is to low to cause botulism unless injected in very high doses.  Per the manufacturer documentation the estimated lethal dose amount that would be 2800 units for 50 % of patients.

Typical treatments are less than 100 units and are thus extremely safe.

Dr. L

Andre Levesque, MD
Austin Plastic Surgeon
4.7 out of 5 stars 3 reviews


 Thank you for your question. Botox use is considered to be fairly safe. The lethal dose is far greater than what is typically used for injection. Sensitivity to different medications  is often related to their clearance by the kidney or liver. Botox is not processed in this manner unless it is injected systemically.

Best wishes
Theodore T Nyame M.D.

Theodore Nyame, MD
Charlotte Physician
4.9 out of 5 stars 38 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.