In patients with Multiple Sclerosis, scalp mesotherapy is not absolutely contraindicated. The procedure is performed locally and does not typically have systemic immune effects. However, safety depends on:– Disease stability (no recent relapse)– Current medications (especially immunomodulatory treatments)– Absence of active infection The concern is not the injection itself, but: risk of infection local inflammation systemic immune stimulation interaction with disease-modifying therapies Scalp mesotherapy for hair loss usually contains: vitamins (biotin, B complex) amino acids peptides sometimes minoxidil sometimes growth-factor-based cocktails If the disease has been stable and the patient’s neurologist does not see a contraindication, scalp mesotherapy can generally be performed with strict sterile technique and careful follow-up.