Can Botox Work for Excessive Underarm Sweating?

Doctor Answers 11

96% chance of working- BOTOX and underarm Sweating

YES. Your odds of 96% are great. In Australia this is partially covered by Medicare, so the treatment is one of the cheapest in the world. 

100u are needed, last up to and beyond 6 months. Takes 90seconds to perform. See the web reference below for more information 

All the best

Dr Davin Lim
Laser and aesthetic dermatologist
Brisbane, Australia. 

Brisbane Dermatologist
4.7 out of 5 stars 77 reviews

Botox for underarm sweating

Thank you for your question. Botox is a very effective treatment for hyperhidrosis (armpit, hands, feet, scalp/face, etc). The dosing is typically based on areas treated but can vary around 50 - 100 units per side depending on how large the treatment area. Duration also depends on dose, but can vary from 3-6 months. For the armpit region, you may also want to consider miraDry as it provides a longer lasting relief.

Young R. Cho, MD, PhD
Houston Plastic Surgeon
4.8 out of 5 stars 38 reviews


BOTOX is formulated with botulinum toxin, a substance that is able to interfere with the transmission of signals sent to glands and muscles. Because hyperhidrosis sufferers are afflicted by overactive sweat glands, BOTOX is able to provide relief by interrupting the processes that cause those glands to secrete more sweat than they should. When this process is interrupted, excess sweating is significantly reduced.  

Jerome Edelstein, MD
Toronto Plastic Surgeon
5.0 out of 5 stars 179 reviews

Botox works great from underarm sweating

I've always been amazed that more people don't do this and that it's not commonly known. Botox works great to dramatically reduce underarm sweating. I find that the effect lasts for about 9 months on average, which is longer than the effect for facial wrinkles. I typically use 50 units per side. Some physicians report the effect lasting only 3-4 months, but I suspect that is because they use less Botox. Another treatment to consider for hyperhidrosis is Precision Tx, a laser procedure done under local anesthesia to ablate the sweat glands.

Douglas J. Mackenzie, MD
Santa Barbara Plastic Surgeon
4.8 out of 5 stars 29 reviews

Botox for excessive sweating

one of he few indications that Botox has been FDA approved for is excessive sweating in the arm pits and palms of the hands. It is called hyperhidrosis and is quite effective, You might get 6 months or a little more out of the injection.

Julio Garcia, MD
Las Vegas Plastic Surgeon
4.8 out of 5 stars 27 reviews

Botox highly effective for underarm sweating

For my patients with severe hyperhidrosis that has impacted their lives significantly, Botox treatment is a life changer! My patients no longer have to worry about being embarrassed, they can wear dark color clothes again, and they don't mind going out to meet new people.

Both Botox and Dysport are highly effective and safe treatment for excessive underarm sweating (hyperhidrosis). Botox has been FDA approved since 2004 for treatment of hyperhidrosis and is widely use for this indication. During your treatment, a topical numbing anesthetic may be applied. Then small injections of Botox is placed directly under the skin of the underarm, usually about 15-20 injections are made to each area. The process takes about 10-15 minutes with minimal discomfort.

Most patients will notice an improvement in about 2-4 weeks. While results may vary, patients will notice at least 6-7 months of improvement. Many of my patients report results up to 9-12 months.

Good luck!

-Dr. Margaret Mann

Margaret Mann, MD
Cleveland Dermatologic Surgeon
5.0 out of 5 stars 1 review

Tired of Sweaty Armpits

Yes, Botox is effective for this condition known as "hyperhidrosis". Be weary however, it is short lived result of a 3-4 months, and requires retreatment with Botox to keep this condition controlled. Recently, Botox has had a few "black box" warnings added to it's FDA label and these are worth reviewing before embarking on chronic recurrent treatment for this condition.

Alternatives to Botox include Drysol - Alum based solution, and iontophoresis. These treatments are not ideal for a variety of reasons.

Steven Hacker, MD
West Palm Beach Dermatologic Surgeon
5.0 out of 5 stars 4 reviews

Absolutely! It is one of the best treatments for underarm sweating.

Thank you for your question.

Botox is an EXCELLENT choice for underarm sweating. The procedure takes about 10-15 minutes and requires multiple injections. The effect lasts anywhere from 3-6 months and the cost can vary depending on how many units are injected into each axilla (generally 25-50 units on each side).

Before you try Botox (a more expensive choice), try using Drysol (Prescription) or Certain Dri (OTC) every night to every other night. That might be a great alternative if it works for you.

Good luck!

Don Mehrabi, MD
Beverly Hills Dermatologist
5.0 out of 5 stars 1 review

Most Certainly

Botox works to stop sweating the same way it works to control wtinkles. It essentially works as an anti-cholinergic. It inhibits the binding of acteylcholine to its intended target, in this case the eccrine gland.

It is recommended that 50 units of Botox be administered into each axilla. Many of us will use Lidocaine to diminish the pain. Also, if one uses a separate 31 gauge needle, the pain is less than allergy testing.

I am not sure if other physicians who adminster this feel the same way, but I have had much longer lasting results when I dilute 2 cc than the recommended 4 cc's. When done in this manner, the reulsts last 9 months, compared to 4-6 months the Allergan prescribed way.

Finally, I would like to mention that this is usually a covered service if one other means of treatment has failed ( usually Drysol but sometimes the anitcholinergic Robinul).

Arnold R. Oppenheim, MD
Virginia Beach Dermatologist
4.7 out of 5 stars 14 reviews

Botox for excessive underarm sweating

Botox works very well for excessive underarm sweating. Quite a few number of units is required (approx 50 per side), but the results last 6 months or longer. Other things to consider include topical aluminum chloride solutions, pills (including Robinul although there are potential side effects) and and iontophoresis (administration of low voltage electricity to the involved areas, probably more appropriate for excessive sweating of the palms/soles).

Good luck.

Bryan K. Chen, MD
San Diego Dermatologist
5.0 out of 5 stars 5 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.