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Oral minoxidil dosing: 5mg once daily versus 2.5 twice daily

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Hi, I’ve consistently used 5mg oral minoxidil to treat my hair loss since January 2022. For a lot of that time, I took the 5mg all at once. Recently I switched to 2.5 in the morning and 2.5 at night. Will this hurt my hair progress? I can’t find any good information about dosing, and my dermatologist suggested it didn’t matter. I’ve seen a chart suggesting 5mg at once causes a higher blood concentration, but minoxidil has a short half life.

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Anna Chacon, MD, FAAD profile photo
Dr. Anna Chacon, MD, FAAD
Answered on Aug 14, 2024
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Dr. Anna Chacon, MD, FAAD
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Jacquelline Leva, DO profile photo
Dr. Jacquelline Leva, DO
Answered on Jan 28, 2025
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