Can native tissue dissolved by hyalase regenerate?

I had hyalase to dissolve restylane 5 years ago which resulted in a much worse large asymmetrical hollow to the bone. Dr. Karamanoukian answered a question about whether hyalase can dissolve native tissue saying that it is possible, while other doctors have replied that it is not possible due to differing ph levels. I would like to ask Dr. Karamanoukian whether he believes the native tissue will ever regenerate? I have tried refilling with more HA but it doesn't take very well. Many thanks.

Doctor Answers 1


It is possible for native hyaluronic acid to be affected by hyaluronidase and it will be replenished over time; however, after 5 years it seems it will not with you and you can have injections to correct the defect

Nashville Dermatologist
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