How Long Until You See Results from Artefill?

Right after two syringes were injected into n/l and marionette lines, I had visible improvement. But after about a week (bruising, etc. subsided), my face looked exactly the same as before. Five weeks now, the same. Is there hope the Artefill will still work in time? If not, why did it fail?

Doctor Answers 6

The Results From Artefill Should be Immediate!

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The results from an injection of Artefill are immediate. The problem is that 20 to 30 minutes later you are likely to get swelling and bruising that will mask those nice results for 7 to 10 days and possibly even longer depending where you were injected.

It should also be remembered that there is not a lot of volume in a any single syringe of a filler. 0.8 to 1.0 cc (the volume of most fillers per syringe) looks like a lot more in the syringe than it actually is. Therefore, with just one syringe on each side, it may well be that you will need some more but you should wait for at least a month to make that decision.

The great news is that, with Artefill, you do not need to refill. In time, if you decide to add more or as you age and you feel you need to add more, you are not having to add the original amount like you would with other fillers that resorb.

I hope that helps. 

Best regards.

Kirkland Plastic Surgeon
4.9 out of 5 stars 64 reviews

Dermal Fillers

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Hello and thanks for the question.


While you should see elements of immediate improvements following resolution of any swelling subsequent to the initial injection, Artefill will incite secondary collagen production  which can take several months to develop. Generally speaking, most patients require no less than two sessions prior to experiencing optimal results with Artefill.  My recommendation would be to proceed with Artefill treatments conservatively as the product will produce a permanent result and changes, as mentioned, will be gradual and evolve with time.


Best of luck,


Glenn Vallecillos, M.D., F.A.C.S. 

Glenn Vallecillos, MD, FACS
Beverly Hills Plastic Surgeon
4.9 out of 5 stars 30 reviews

Artefill is always done in at least 2 sessions 3 months apart.

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Don't expect to see great results from artefill with only 1 session.  It almost always takes at least 2 sessions about 3 months apart and the results will be evident about 6-9 months later.

David Hansen, MD
Beverly Hills Dermatologic Surgeon
4.7 out of 5 stars 46 reviews

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You must go slow with Artefill

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Artefill results are permanent, but require your body to respond to it to form the collagen. Everyone is different and responses differ. Most people get 2 sessions and see great results in a few weeks, but I would give it 6 months to judge the two sessions. It is easy to add, but cannot be subtracted!

Mary P. Lupo, MD
New Orleans Dermatologist
5.0 out of 5 stars 18 reviews

Artefill works (if done correctly)

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FIrst of all, correction with Artefill is almost never done in one session to avoid the complication of over-correction. My patients usually are booked for two sessions two months apart. The rare patient will need three sessions. Most of the correction is achieved in the first session and for nasolabial folds that means two syringes.

Second, 80% of what's injected with Artefill is cow collagen and is resorbed. Only 20% of the remaining volume is the permanent particles of PMMA. The patient's own body then forms human collagen capsules around each particle, thus restoring that other 80% with the patient's own tissue.

So why would could that "fail"? Several reasons, but the most common would include delayed or impaired collagen formation (e.g., a patient on corticosteroids like prednisone) or injection too deeply, such as into the deep fat of the face.

Injection of Artefill requires thorough knowledge and experience with skin anatomy and with injection techniques. The vast majority of problems I've seen with patients who've had fillers are problems that are--as we say--"proximal to the syringe"--a fancy way of saying that the problem was the person injecting it, not the patient getting the injection.

Make sure, though, that if you return to the surgeon who did it that you compare your appearance with your pre-injection photos... it's possible that there actually has been some improvement.

All the best,


David C. Pearson, MD
Jacksonville Facial Plastic Surgeon

You treat the area until you reach the correction you desire

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When injecting Artefill, you treat the area until you reach the correction you desire, so you will see the results right away. But, the results will continue to improve because the product stimulates the production of your own collagen over time.

Joseph A. Eviatar, MD, FACS
New York Oculoplastic Surgeon
4.7 out of 5 stars 68 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.