The problem is that Botox is rapidly incorporated into the nerve - minutes to hours. It then "kills" the nerve endings so the muscle that it is attached to won't contract. New nerve endings then grow and the movement returns. There is no pathway to reverse it unless it is done immediately to prevent the absorption of the Botox. I believe there is a product out there for people who are overdosed but as I said, it needs to be administered very rapidly. It would be done before the "effects" of the Botox were noticeable. Drooping of the eyelid from Botox is extremely rare in experienced hands, eyebrow ptosis is somewhat more frequent.
The research is still on going for a Botox inhibitor and there is no anticipated date of release. Botox is a fabulous injection but there is always a risk of side effects no matter how small with any injection. Best, Dr. Green
Thank you for your question Fifienne. Botox is a purified protein used to address wrinkles associated with facial expression. A rare side effect is droopy eyelids. This occurs if the Botox moves to the muscles which raise the upper eyelid. Such a side effect is temporary and treatable. Droopy eyelids usually resolve in 2-4 weeks, but sometimes it could take 3-4 months. This can be treated with apraclonidine 0.5% ophthalmic solution 2-3 drops per eye 2-3 times per day. Comparing Botox to Russian roulette is like comparing apples and oranges. Death from Russian roulette is different from temporary droopy eyelids after Botox. With any treatment there are risks. It is important to understand the risks, benefits, and alternatives of any treatment before undergoing it. In our office all patients undergoing any treatment are required to sign an informed consent prior to the treatment. The signature indicates that they understand the risks and are willing to take the risks associated with the treatment. Sometimes patients are not willing to take the risk and they do not undergo the treatment. I am not aware of any ongoing research to find an antidote or inhibitor for Botox. Please follow up with your doctor for specific recommendations. Good luck!
While you might read about Botox inhibitors, these are really just in the experimental phase and only have theoretical applications.
I doubt very much that a Botox inhibitor will ever be marketed and available for retail use as it has many serious implication. Given your apprehension about Botox, I strongly recommend you consult a facial plastic surgeon about surgical options to achieve your cosmetic goal.
A medical check of your eyes and brow area may reveal some underlying anatomy or muscular problem that is making you more at risk for a droop.
Sometimes patients have pre-existing weak eyelids (ptosis) or brows that needs altered Botox doses.
Good idea. As always, if people donate for medical research or write to their Congressman to support NIH research, a lot of medical problems can be solved quicker than later.