Is Botox Mixed with Any Other Solution for Hyperhidrosis?

Do you mix Botox (100mg) with any other solution for treatment of hyperhydrosis on the scalp and head?

Doctor Answers 9

Botox for hyperhydrosis

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Thank you for your question. Botox is a very effective treatment for hyperhidrosis (armpit, hands, feet, scalp/face, etc). The dosing is typically based on areas treated but can vary around 50 - 100 units per side depending on how large the treatment area.  Botox is not mixed with any other product other than the saline used to reconstitute Botox.   Duration also depends on dose and technique, but can vary from 3-6 months. For the armpit region, you may also want to consider miraDry as it provides a longer lasting relief and in the long run is more cost-effective.

What is Botox mixed with...

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Botulinum toxin such as Botox is a freeze dried powder to which saline (preserved or non-preserved) is added so as to reconstitute it and be able to administer it via syringe. It has been used for over 20 years on the market very safely and effectively for many indications, including hyperhidrosis/excessive sweating.

Benjamin Barankin, MD, FRCPC
Toronto Dermatologic Surgeon

Botox needs to be mixed before administration

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botox is ver effective for hyperhydrosis but also consider miradry for under arm sweating.  Its  FDA approved and long lasting

Cameron Rokhsar, MD, FAAD
New York Dermatologic Surgeon

Botox dilution for hyperhidrosis

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Botox comes as a fine white powder in a vial.  One has to mix it with sterile saline to get it into injectable, (liquid), form.  There are no other recommended liquids for dilution at time of this writing.

Jeffrey J. Roth, MD, FACS
Las Vegas Plastic Surgeon
4.6 out of 5 stars 17 reviews

Botox used for increased sweating / hyperhidrosis

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No. The only approved diluent for the Botox powder is sterile saline (salt water). If a doctor mixes it with any other product, the effectiveness and safety, and comfort level during the administration can not be assured.

Ronald Shelton, MD
Manhattan Dermatologic Surgeon
4.9 out of 5 stars 38 reviews

Botox for Hyperhidrosis

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Botox is supplied in 100 unit vials.  Regardless of its intended injection site Botox is always mixed with sterile saline.  The concentration is usually less for Hyperhidrosis than for facial wrinkles.

Mixing Botox for hyperhydrosis

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Botox is reconstituted with sterile saline prior to being use for treatment of dynamic facial wrinkles and for treatment of hyperhydrosis of the underarms, scalp, hands and feet. I know of no other solutions recommended for use in the reconstitution of Botox.

Botox dilution

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Botox is diluted in sterile saline solution to allow for injection.  Other than that, it is not mixed with any other solution ( i.e lidocaine, etc..) 

Steven Wallach, MD
New York Plastic Surgeon
4.2 out of 5 stars 30 reviews

Mixing Botox

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 Botox comes as a fine white dust in its bottle and is reconstituted with saline prior to use.  I am not aware of any difference in this regardless of where you are going to use it.

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.