What's the difference between Botox and Dysport?

Wondering what, if any, differences are between Botox and Dysport? Is one stronger than the other? Does one take effect sooner or last longer? Thanks!

Doctor Answers 22

The Difference Between Botox and Dysport

Thank you for your question. Botox, Dysport and Xeonim are the three neuromodulators available to help smooth out wrinkles. There length of duration is the same for all three products. The onset for Dysport can be a day or two faster. Dysport dosing is different than Botox, it requires 2.5-3x more. 

Summit Emergency Medicine Physician
5.0 out of 5 stars 22 reviews


Botox, Dysport and Xeomin contain the active ingredient called botulinum toxin type A. Botulinum toxin type A blocks certain nerves from communicating with muscles and other organs like sweat glands. The differences are in the other materials that they contain. Both Botox and Dysport have carrier proteins. Xeomin is the purest of the toxins.

Omeed Memar, MD, PhD
Chicago Dermatologic Surgeon
4.9 out of 5 stars 32 reviews

Botox vs. Dysport

Both are very similar types of neurotoxin that relax muscles.  The biggest difference is that Dysport is a smaller molecule which means it has a higher tendency to "travel" after injection.

In experienced hands, this is not an issue, although in other cases, it can spread more easily to areas not intended.  We typically stick with Botox for this reason, since it has a very predictable result.

Reza Tirgari, MD
San Diego Physician

The difference between Botox and Dysport

Thank you for sharing your question. Botox, Xeomin, and Dysport are all neuromodulators that are used for the treatment of fine lines and wrinkles on the face. Each product contains the same active ingredient and has the same mechanism of action. Overall, these products are very similar and are used relatively interchangeably in most practices. Some patients report varying onset time intervals and longevity of effects for each product, however these factors largely depend on the individual person. It is of paramount importance, however, to ensure you are seeing an experienced injector for your treatment, regardless of the product being used. To learn more about which product is right for you, I recommend consulting with a board-certified specialist. Best of luck. 

Kian Karimi, MD, FACS
Los Angeles Facial Plastic Surgeon
5.0 out of 5 stars 60 reviews

Dysport may last 1 month longer than regular botox in half of the patients and may kick in sooner as well.

Dysport is probably getting more attention now that it has been out a long time just like regular botox. It may last 1 month longer than regular botox (4-5 months vs 3-4 months) in half of the patients. It does kick in a few days quicker also. They generally run the same price.

David Hansen, MD
Beverly Hills Dermatologic Surgeon
4.8 out of 5 stars 37 reviews

Botox and Dysport differences

Thanks for your question. Differences may exist but are still being studied and debated. It’s best to consult with a board certified dermatologist to determine

which option is best for you. Injection technique may also be more important than the product injected. Best, Dr. Katz


Bruce E. Katz, MD
New York Dermatologic Surgeon
3.8 out of 5 stars 17 reviews

Difference between Botox and Dysport

Botox and Dysport are different brands of neuromodulators and are both used to smooth lines, lift eyebrows etc. 1 Unit of Botox is comparable to 2.5 Units of Dysport. Dysport difuses (spreads) a little more than Botox so it will need to placed a little different than Botox. Dysport it comes on a little faster and some people feel it lasts longer. 

Renata Wix-Harris, MD
Livingston Physician
5.0 out of 5 stars 1 review

Dysport lasts longer then Botox for most patients

Botox and Dysport are both great products. They are nearly identical; both are Botulinum toxin type A, purified from the Clostridium botulinum bacterium. Minor differences result from the manufacturing process.

In my experience, most patients get 4 months or more duration from Dysport injected into the corrugator supercilii muscles, the muscles that makes the vertical "11's" between the eye brows. About 20% of patients actually get 6 months' effect. I find that Botox lasts 3-4 months at an equivalent dose, so Dysport usually lasts longer.

Both can be used in multiple areas of the face. I see no difference in side effects: no allergic reactions; well under 1% eyelid droop for both. Dysport also starts working a little faster than Botox and diffuses, or spreads out, a little bit more than Botox, so it can look a little more natural in the forehead.

Most doctors prefer Botox or Dysport based on their experience and preference. I do think that some doctors overemphasize their preference, especially if they use only one in their practice. Generally, it's best to find a doctor familiar with both.

Xeomin is the third FDA-approved Botulinum toxin. It is also similar but may not last quite as long as Botox or Dysport.

Thanks for your question.

Steven Goldman, MD
Cleveland Plastic Surgeon
5.0 out of 5 stars 118 reviews

Botox and dysport

While they are slightly different products, in general they will produce the same results. Best of luck with your decision to move forward.

Steven Wallach, MD
New York Plastic Surgeon
4.1 out of 5 stars 24 reviews

What's the difference between Botox and Dysport?

Hello Sweetness401,

That is an excellent question and there really isn't much of a difference between Botox and Dysport.  Botox is made by Allergan (same company that makes Juvederm and Kybella) and Dysport is made by Galderma (company that makes Restylane, Silk, and Lyft).  They both are great.  The dosing is different but comparable.  Dysport tends to be more affordable and my patients that prefer it say it comes on faster and does last longer.  Botox is more of the name brand and has more market share.  I've injected both on my family with great results.

I hope this helps and good luck. 

William Marshall Guy, MD
The Woodlands Facial Plastic Surgeon
5.0 out of 5 stars 25 reviews

These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.