SoCal Plastic Surgeons - Upland

SoCal Plastic Surgeons - Upland

4.9 rating from 417 reviews
Practice Information
409 N. Mountain Ave., Ste. A, Upland, California

About the Practice

Doctors & Other Staff Members

Matthew J. Nykiel, MD
Board Certified Plastic Surgeon
4.9

795 Before & After Photos

417 SoCal Plastic Surgeons - Upland Reviews

Persistent782654
Lipo 360 BBL•22 days post-op•May 29, 2025
Amazing Experience!
KKnechtt
Breast Lift with Implants•2 months post-op•May 11, 2025
Best Decision Ever
allana85
Breast Augmentation•2 months post-op•April 23, 2025
Thank you for making this such a positive experience!
Helpful197947
Semaglutide•4 months post-op•April 13, 2025
Lost 25 Pounds with Semaglutide – So Grateful!
AdrienneMatson
Dysport•9 days post-op•April 10, 2025
Dysport is Worth the Hype!
AdrienneMatson
Breast Augmentation•1 month post-op•April 9, 2025
Amazing Results, Minimal Downtime.
Persistent227037
Tirzepatide for Weight Loss•5 days post-op•April 5, 2025
Best Experience Always
Awesome421642
Brazilian Butt Lift•2 months post-op•March 31, 2025
bbl 360 and lipo
tifffyy
Breast Augmentation•2 months post-op•March 19, 2025
Amazing Result and Experience with the Office and the Dr
tristianperz
Kybella•13 hours post-op•March 11, 2025
My Visit Was Great!

309 Answers

A Thanks for the great question! Fat transfer traditionally involves removing fat from one part of your body and injecting it into areas that need more volume—common examples include the face and buttocks. One of the key benefits of using your own fat is that it contains live stem cells, which may help improve skin texture and overall appearance. However, not everyone has enough fat available for transfer. In these cases, we now have allograft fat options—donor fat from another individual. In the U.S., there are currently two main FDA-approved products: 1. Renuva FDA Approved: 2021 Longevity: Reported to last up to 10 years Processing: The fat is processed to retain the extracellular matrix (ECM)—a structural framework that supports fat regeneration—but does not contain live cells Consistency: Very smooth, allowing for precise injection into facial or superficial fat layers Volume: Comes in small syringes (3cc), making it ideal for smaller treatment areas like the face or hands 2. Alloclae FDA Approved: 2025 Processing: Uses X-ray sterilization, preserving both the ECM and the cell wall - cellular components are removed, which may provide added regenerative benefits Texture: Firmer than Renuva—designed for use in larger-volume body areas, not the face Volume: Available in larger sizes (12.5cc and 25cc), making it more practical for body contouring Longevity: Still being studied, but early expectations suggest similar duration to Renuva—however there is a difference in processing - so the longevity may be the same, worse, or better. In summary: If you have enough of your own fat, it’s usually preferred because of the added skin-rejuvenating benefits. But for patients without sufficient donor fat, Renuva and Alloclae offer exciting alternatives, each with unique advantages depending on the treatment area and goals.
Answered by Dr. NykielJune 5, 2025
A Great question! I would recommend the micro-fat transfer to the face. Here’s a simple breakdown of the key differences between Micro Fat, Alloclae, and Renuva: Micro Fat This is fat taken from your own body and then processed into very small particles. Because of its size, micro fat can be placed more superficially, making it ideal for facial areas. One of the biggest benefits of using your own fat is that it contains stem cells, which may help improve skin texture and overall skin quality in the treated areas. Alloclae Alloclae is processed donor fat (from another individual). It’s a thicker, firmer product and is not designed for use in the face. It does not inject smoothly and is better suited for larger-volume areas like the body—not for creating natural, refined facial contours. Renuva Like Alloclae, Renuva is also derived from donor fat but is processed to be smooth and injectable for facial applications. However, unlike your own fat, Renuva does not contain live cells or stem cells, so it won’t provide the regenerative benefits associated with your own micro fat. In summary, if you're looking for skin quality improvement and natural facial volume, micro fat is typically preferred due to the presence of your own stem cells. Renuva is a good alternative if you’re not a candidate for fat harvesting, while Alloclae is better for body contouring—not the face.
Answered by Dr. NykielJune 5, 2025

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