This is day 5 since having my first xeomin injections. To start with, I am a male so it was a little harder to find much info from a mans perspective so this is my experience. Hope it helps. I have severe migraines and that's why I tried xeomin. It's the pure form of Botox (none of the additives that Botox has.) since having the injections I wake up feeling refreshed. No headaches so far. The injections feel about like plucking an eyebrow. Not very painful. I have one small bruise under my eye which is almost gone now. My skin looks and feels amazing. No wrinkles anymore. It started to really take effect about day 3 and I would say it's fully kicked in now. I still have movement ( not frozen). I had my treatment at The Sculpting Spa in Cookeville TN. They were very great and the injections are administered my a MD.