A As we age, we lose volume in our face, which occurs for a variety of reasons. Losing weight could actually accentuate your nasal labial folds because your skin is supported by fat and subcutaneous tissue, therefore losing facial fat could mean losing support and result in further folding of your skin. Fillers are great because they work immediatelly to return volume to volume depleted areas of the face which lift the skin and fill out folds and depressions, resulting in a more rested and youthfull appearence. There are also many types of skin tightening devices that are great at tightening the skin, but not necessarily volumizing the face. The combination of both dermal fillers and lasers are the best way to age gracefully. I hope this helps.