Restylane to Smile Lines

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Long term follow up on Restylane. The before is 11/2006. The patient received 3cc's of Restylane total (11/06, 5/07, 11/07). The after photo is 2/2012 (4.5 years after the last treatment). Restylane is known to cause collagen remodeling in the skin (your body repairing its own wrinkles with its own collagen in response to Restylane) and most if not all of this long term improvement is probably a result of that affect.