{"id":25751,"date":"2023-09-25T10:23:00","date_gmt":"2023-09-25T17:23:00","guid":{"rendered":"https://www.realself.com\/news\/?p=25751"},"modified":"2024-02-16T09:29:14","modified_gmt":"2024-02-16T17:29:14","slug":"profhilo-new-injectable-skin-booster","status":"publish","type":"post","link":"https://www.realself.com\/news\/profhilo-new-injectable-skin-booster","title":{"rendered":"Will Profhilo Live Up to the Hype? Doctors Weigh In on the Injectable Skin Booster That\u2019s Coming to the U.S."},"content":{"rendered":"

It’s rare that an entirely new category of injectables hits the scene, so it’s understandable why the industry was set abuzz when the concept of skin boosters<\/a> made its way to the U.S. (To be fair, it’s a category that has been available internationally for quite some time but is just now starting to make an appearance stateside.) Like many dermal fillers<\/a>, these injectables utilize hyaluronic acid (HA)—but in a very different way. Rather than adding volume and changing the contours of the face, this new category is meant to subtly and naturally enhance skin quality. These fillers are like moisturizers that work from within the skin, adding a plumpness, radiance, and generally youthful glow to your complexion without changing your face shape. Juvéderm’s Skinvive received FDA approval earlier this year<\/a>, but Profhilo is another product that has both consumers and doctors really excited. Will it live up to the hype? We asked three doctors for their predictions.<\/p>

What is Profhilo?<\/h2>

“Profhilo is made of non-cross-linked hyaluronic acid. Cross-linking is what keeps our body from breaking down the hyaluronic acid, but it’s also what gives fillers thickness and viscosity,” explains Dr. Konstantin Vasyukevich<\/a>, a board-certified facial plastic surgeon in New York City. In short, the more cross-linked an HA filler is, the more dense it is. The options on the market now all have varying degrees of cross-linking, which is why some of them are thinner and used for more delicate areas like the lips and under the eyes (Restylane Silk<\/a>, for example), while others are much thicker and more appropriate for cheeks and jawline (Juvéderm Voluma<\/a>). Because Profhilo isn’t cross-linked, it’s extremely fluid; rather than adding volume or structure, it delivers more of an overall plumping effect, giving the skin a youthful glow, adds Dr. Vasyukevich. “Think of it as an internal moisturizer that not only gives you hydration but may also have an impact on elasticity and crepiness, improving overall skin texture,” adds Dr. Amelia Hausauer<\/a>, a board-certified dermatologist in Campbell, California.<\/p>

Skin boosters are also injected differently from traditional HA fillers. Rather than being placed in large amounts deep within the skin, boosters, Profhilo included, are injected in smaller amounts and more superficially. Typically, this also means there are way more injection sites, although Profhilo is a little bit different from some of the others (more on that point in a moment). <\/p>

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Profhilo vs. Skinvive: What are the differences?<\/h2>

Both are hyaluronic acid skin boosters, meant to impart the same types of benefits—improving overall skin quality rather than adding volume or fullness. To that point, New York City board-certified dermatologist Dr. Paul Jarrod Frank<\/a> anticipates that the two will eventually become somewhat synonymous, much like the different brand names of neurotoxin (Botox\/Dysport\/Xeomin). “The formulas will be slightly different and individuals may notice subtle nuances, but the main intent and result are the same,” he says.<\/p>

Still, Dr. Hausauer adds, there are some noteworthy differences in the formulations—although she agrees that the benefits will likely be very similar. “Profhilo contains the highest amount of hyaluronic acid on the market, 64 mg\/ml compared to Skinvive’s 12 mg\/ml,” she explains. The hyaluronic acid in Skinvive is also cross-linked, (minimally so, because, again, it is still very thin and meant to be used as a skin booster), but Profhilo isn’t at all, she adds. And whereas skin boosters are typically injected via multiple superficial injection sites in a grid-like pattern across the face, Profhillo is meant to be injected in a fewer number of spots that are strategically chosen based on how the product diffuses and spreads under the skin, she explains.<\/p>

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