A Drain-Free Tummy Tuck With TissuGlu Awaits

The pain and discomfort associated with drains is the No. 1 complaint of abdominoplasty patients.1

Drains are awkward, cumbersome, and can be difficult to hide under everyday clothing. They can be messy and leak onto your clothes, especially during your required drain maintenance. Some patients require postoperative drains for one to three weeks, significantly interfering with their ability to return to normal activity and work.

TissuGlu® Surgical Adhesive helps transform recovery into a less invasive, more comfortable experience, freeing you from drains and the risk of drain-related infection.

Return to being you more quickly without worrying about drain-related scars and additional procedures to remove drains. Best of all, you won’t have to deal with ugly, burdensome drains that require special care while you heal from a major surgery.

Hear About TissuGlu

How TissuGlu Works

During the tummy tuck procedure, TissuGlu drops are applied in a precise grid pattern with a special applicator. Once applied, TissuGlu forms a strong bond to hold tissue layers together, reducing spaces between layers where fluid may collect. TissuGlu helps your body to resorb fluid naturally and recover from your tummy tuck without drains.

TissuGlu applicator

TissuGlu is the first FDA-approved surgical adhesive for internal use, combining strength and safety to give you the advantage of a clinically proven alternative to drains. TissuGlu safely breaks down and is eliminated naturally from your body.

Get the TissuGlu Advantage

  • Return to your everyday routine more quickly2

  • Avoid the pain and discomfort caused by drains—no drain emptying, fluid measurement, or maintenance required

  • No drain-related stress and burden on you and your caregiver during recovery

  • Reduce anxiety about the procedure and aftercare related to drains

  • No worries about additional scarring caused by drains

  • Peace of mind knowing your risk of drain-related infection is eliminated

You may feel so good after your tummy tuck that you want to do more than your healthcare provider has recommended, but remember you just had a major surgery and your body needs time to heal.  

Reference: 1. Data on file, Cohera Medical, Inc. 2. Hunstad JP, Michaels J, Burns AJ, et al. A prospective, randomized, multicenter trial assessing a novel lysine-derived urethane adhesive in a large flap surgical procedure without drains. Aesthetic Plast Surg. 2015;39(4):616-624. 

Always consult your healthcare professional for specific advice related to your medical conditions and treatment, including all risks and potential benefits of undergoing this treatment. Only your healthcare professional can assess whether you are an appropriate candidate for this procedure.

This guide has been reviewed for accuracy and bias by Dr. Alexander Nein, a Nashville plastic surgeon and independent expert. Learn more about Dr. Nein. It has also been vetted by the RealSelf Editorial Team for adherence to our Brand-Sponsored Content Guidelines.

Important TissuGlu® Surgical Adhesive Safety Information


TissuGlu® Surgical Adhesive is indicated for the approximation of tissue layers where subcutaneous dead space exists between the tissue planes in abdominoplasty.


Do not use in patients with known or suspected allergies to urethane-based or isocyanate-containing products.


  • Do not use TissuGlu® Surgical Adhesive in patients who have had prior exposure to TissuGlu®. Immunological response associated with repeat TissuGlu® exposure has not been studied.

  • The effectiveness for the treatment of patients with BMI > 28 has not been established. Higher BMI patients have a propensity for fluid accumulation and may have an increased risk of seroma formation.

  • Effectiveness was not observed in weight loss patients undergoing abdominoplasty. Weight loss patients have a propensity for fluid accumulation and may have an increased risk of seroma formation and aspiration.

TissuGlu® may reduce the need for drains after surgery. By using TissuGlu® instead of drains, you may:

  • Return to normal activities more quickly

  • Experience less discomfort and pain than when drains are used

  • Have fewer invasive treatments for fluid management. The results showed that 73% of TissuGlu® patients had no treatments after surgery. However, some patients did require additional invasive treatments including reinsertion of drains.

Clinical studies were performed using TissuGlu®. There were no increased safety risks with the use of TissuGlu® than when drains were used. Potential complications associated with the use of the device and the tummy tuck procedures include seroma (fluid) formation. These complications may require treatments such as drain placement and/or fluid removal by needle, which may be performed in the operating room. Additional potential complications include wound healing issues, rash/redness, surgical site or incision infection, scarring, hematoma (bruise or swelling), incision separation, and immunological reaction.

Safety Information: 
For full safety information please visit http://tissuglu.com, contact your doctor, or call Cohera Customer Support at 1-800-641-7458.

TissuGlu® Surgical Adhesive is currently approved for sale in the United States for the approximation of tissue layers where subcutaneous dead space exists between the tissue planes in abdominoplasty. TissuGlu® Surgical Adhesive received European CE Mark in 2011, where it is approved for large flap surgical procedures such as abdominoplasty. TissuGlu® Surgical Adhesive is not approved for sale in any other region. Any questions related to the indication for use should be directed to your doctor or to Cohera Medical Corporate Clinical Affairs. Refer to the complete TissuGlu® Surgical Adhesive Directions for Use for prescribing and usage information.

Sponsored by