I got botox for the first time 02/14/09. Nothing too painful at all.I had an awful "1" line. He injected about 16 shots (forehead, between eyes)and even put 2 small injections in my one eyebrow (that eye always drooped). It is now 5 days later and while I can see about 50% improvement, that pesky "1" line is there, not as strong, but there. Called doctor and he said it takes a full 7 days, but had me make another appointment on 02/28 (14 days later) just in case I need more! I am happy, but not over the moon with my results. I talked to my friend and she suggested her doctor, so in 3 months I'll go to that doctor.