I always tell my patients that it takes about three to four days to begin to see a result from a Botox or Xeomin treatment. The treatment effects will max out in about 10 days and I invite all of my patients to come in at ten days so we can evaluate the effects. If they need a few additional units I usually provide them at no cost. Twenty units is usually a sufficient amount but if the vertical frown lines are deep it often takes a wrinkle filler such as Restylane to make them go away. Using a wrinkle filler and Botox or Xeomin extends the life of the wrinkle filler.