Irvine Dermatologic Surgeon
16100 Sand Canyon Ave, Suite 190
Irvine, California 92618 US
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Treatment Pricing

Specials and Deals

Free Botox Trial
$150 Off
$150 Credit on Fraxel for Face
$150 Off
$150 Credit on Thermage 1200 P
41K profile views
38 years experience
811 expert answers
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"Dr. Pilest and Laura did such a wonderful job transforming my skin and I am so grateful!"

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4.6 out of 5 stars 4.6 stars from 23 reviews See details Hide details
5.0 out of 5 stars Doctor's bedside manner
5.0 out of 5 stars Answered my questions
5.0 out of 5 stars After care follow-up
5.0 out of 5 stars Time spent with me
5.0 out of 5 stars Phone or email responsiveness
5.0 out of 5 stars Staff professionalism & courtesy
5.0 out of 5 stars Payment process
5.0 out of 5 stars Wait times
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5 out of 5 stars Botox

The Best Preventative Maintenance!

Dr. Nissan is the head training doctor for Botox at Allergan in Irvine, where Botox was developed. He has a very gentle hand and an amazing amount of experience.

5 out of 5 stars Latisse

Love Latisse! - Irvine, CA

I go to Total Dermatology in Irvine and really like it - very professional and the Dr. has a lot of experience.

5 out of 5 stars Restylane

Wouldn't Go Anywhere Else! - Irvine, CA

Dr. Pilest is the only Doctor I trust to perform any of my injections. I don't do much but the tweaks here and there are so natural and make me look like a more rested and prettier version of myself. Today I got undereye filler and Xeomin! I love the immediate results of the undereye filler! I will definitely be back for all of my dermatology needs!

5 out of 5 stars Botox

Dr. Pilest is an injection artist!

What an amazing experience! Everyone is so friendly and helpful. Ana and Sandy prepped me for injections, and made sure I was comfortable. Dr. Pilest...I cannot thank you enough. You are a miracle worker!! I am sooo happy!

1 out of 5 stars CoolSculpting

Cool sculpt FAIL :(

Very nice staff however I got cool sculpt and it did not work :( I got 2 treatments, spent thousands of dollars and I saw absolutely zero results. I'm not sure if they just don't know how to do it or if they need new machines but it was a total waste of money and a lot of discomfort to go through for no results.

5 out of 5 stars Injectable Fillers

Best Dr. ever! Treatment for Lips and Smile Lines.......

Amazing!! Dr Pilest is the BEST. He is so nice and friendly and his staff is very helpful. They really take time to make you feel comfortable and listen to your needs. My lips are noticeably fuller but look completely natural. They are perfect I am sooooo happy with my results. I had my lips done once previously by my plastic surgeon and it was extremely painful, I bruised and experienced a...

5 out of 5 stars Botox for Migraines

Excellent! Highly recommend

Treatment: botox for pain. Dr is professional, understanding,responsive, very nice. He helps me. All his staff is friendly, helpful, always greet you with a smile ready to help. The office is state of the art.

5 out of 5 stars Skin Tightening

Patient for life - Irvine, CA

I've been there 3 times. The staff and Doctor Nissan Pilest were fantastic. I'll be back for my regular tune up soon. Keep up the great work Total Dermatology!! If your shopping around looking for a great Dermatology , look no further.

5 out of 5 stars Fraxel Laser

Dr Pilest Is The BEST!!!

Thank You Dr. Pilest for being there for us who need your gifted services. Its been 10 yrs since I last visited and was treated with the fraxel laser for my acne scars which I only did one session. At 55 now, I would not go anywhere else, it's a Win Win situation as you offer the best treatments and products available to us today. Just had my 1st new fraxel done in May and love love the...

1 out of 5 stars Injectable Fillers

Aquagold Fine Touch. Irvine, CA

He's a nice guy. He means well I'm sure. The nurse actually performed the procedure. She was super nice and personable. The office manager isn't that great. I called to let them know I was unhappy. Jamie called me back. She said she's sorry I was unhappy and said she could schedule a follow up but gave me the impression I was out of luck on any kind of reimbursement or another procedure offered. I cancelled my follow up appt. It is what it is I guess.

*Your results may vary. Any specific claims or permanence length of results vary for each patient and are not guaranteed.

Personal Statement

Nissan Pilest, M.D. is a Board-Certified Dermatologist with over 37 years experience in Corrective, Cosmetic, and Surgical Dermatology. Dr. Pilest is an Assistant Clinical Professor of Dermatology at the University of California Irvine.

Board Certifications

Board-certified by the American Board of Dermatology


American Academy of Dermatology (AAD)
American Society for Laser Medicine and Surgery (ASLMS)
American Society of Dermatologic Surgery (ASDS)

Consultation Fee

$100. Consultation fee may be applied towards any treatment rendered within 30 days of visit.

Awards & Recognition

Top Doc 2015 Orange County Medical Association
Expert Injector, 2014-2016
Volunteer Appreciation Faculty of UCI
Orange County Register and Coast Magazine Physicians of Excellence, 2015
RealSelf Top Doctor

Hospital Privileges

Dr. Pilest has hospital affiliations at UCI.


  • Undergraduate & Medical School

    Medical: MD in Dermatology from the University of Arkansas

Treatments offered at Total Dermatology

Most popular answers from Nissan Pilest, MD

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Does Latisse Work Better Than Revitalash?

Before the FDA approval of Latisse, Revitalash and another product named LashMD both came on the market for the purpose of lengthening and thickening... READ MORE

Will Restylane Be Damaged by IPL or Refirme?

Generally Thermage or IPL or other nonablative lasers dont effect Fillers such as Restylane or Juvederm however if it is possible do the filler... READ MORE

What is the Proper Maintenance After Fraxel Treatment is Complete (5 Treatments)?

Remember that your skin is still healing internally for about 4 to 6 weeks after your series of treatments are complete. Your skin is also more... READ MORE

Is micro needling with hyaluronic acid as effective as micro needling with PRP?

The act of microneedling alone is stimulating collagen and elastin, so you will likely see results regardless of what solution is applied topically... READ MORE

Is there something I can buy over the counter that works like tazorac?

Unfortunately there is nothing over the counter that matches the efficacy of Tazorac. Tazorac is the name brand of a prescription retinoid.... READ MORE

Is hyaluronidase the best option or should I just wait for the restylane to leave my body on its own? (Photo)

I am sorry to hear you are disappointed with your Restylane under-eye treatment. The positive thing about hyaluronic acid based fillers such as... READ MORE

What EXACTLY happen to the fat and how is it "eliminated" after CoolSculpting?

A Coolsculpting treatment uses a method called cryolipolysis (fat freezing) once the fat is frozen it goes through apoptosis (programmed cell death).... READ MORE

How can you thicken skin under the eyes, especially tear trough area? I heard fraxel and Thermage are good. What about creams?

Youthful skin is full of collagen and elastin fibers making the skin firm and tight. As we age so does our collagen and elastin and we stop creating... READ MORE

Aging neck - will Sculptra do the trick (Ultherapy sounds painful!) If yes, how much is required?

I would recommend a combination of fillers and a radio-frequency treatment. If you inject fillers on the jawline it will give your jawline more... READ MORE

Does Proactiv really work to clear acne?

Proactiv is an over the counter product, this system uses ingredients like benzoyl peroxide to help treat the bacteria and inflammation in your skin.... READ MORE

Before and After Photos by Dr. Pilest

Nissan Pilest, MD has shared 144 before and after pictures with 1,065 helpful votes from the RealSelf community.

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Videos by Nissan Pilest, MD

Nissan Pilest, MD has shared 4 videos.

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eMatrix: A Non-Laser Skin Resurfacing Option for All Skin Types

Dr. Nissan Pilest demonstrates an eMatrix treatment, which is radiofrequency-based skin resurfacing that is safe for all skin tones. Through a series of treatments, eMatrix can improve acne scars, pigmentation, fine lines, skin tone and texture. WATCH VIDEO

Watch This Woman's Kybella Treatment to Dissolve Her Double Chin

Kybella is the first FDA approved injectable for dissolving fat under the chin, commonly referred to as the "double-chin." Dr. Nissan Pilest demonstrates the procedure on this woman. WATCH VIDEO

eMatrix Resurfaces the Skin Without Lasers — See For Yourself!

Dr. Nissan Pilest harnesses radio frequency with eMatrix and uses platelet-rich plasma (PRP) injections to resurface this young woman's skin and remove old acne scars. WATCH VIDEO

Fill Me In: Learn What's to Come in the World of Fillers

Fillers have come a long way in recent years. Dr. Nissan Pilest discusses the 10 different fillers currently on the US market. WATCH VIDEO

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*Your results may vary. Any specific claims or permanence length of results vary for each patient and are not guaranteed.