I've been getting what my husband calls "female maintenance work" done by my derm for almost 10 years now, starting with Botox on the brow and microderms 4-5/x year and now have added Perlane for the naso-labial folds. The first time I tried Perlane I was initially worried that I'd made a mistake as the area was actually hard to the touch for about a month after the procedure. Then it softened and I LOVED the smooth fullness it gave me, really making me look younger in a very subtle way. And it lasted almost exactly a year! I suggest you try it; my doc says its better for the folds than Radiesse (molecules are really to big with Radiesse, apparently) but be prepared for swelling, bruising and a few weeks for it to soften and settle. THEN you should LOVE it!