This is an interesting question! If I understand correctly you are asking if it is safe to apply sculptra (instead of PRP or hyaluronic acid) to the skin during micro needling of skin.
Theoretically this makes sense and this is a smart thought.
In my opinion it’s best to inject sculptra into deeper layers and do PRP micro needling to top of the skin. One can add ACell, an extra cellular matrix, which promotes stem cell induction and regeneration of top layer of skin.
Sculptra promotes collagen formation in the connective tissue. It requires aggressive massaging for at least 5 days to make sure results are not “bumpy”. This is because collagen deposits may not be evenly distributed and the massage helps even out the results.
First problem is that after micro needling the skin will be sensitive in healing stage and frequent massage may be a challenge.
Secondly bumpy results of sculptra is better tolerated in deeper tissue and camouflaged by epidermis. But micro needling will place sculptra in outermost layer of skin and you don’t want to take the risk of having bumpy skin.
I would probably try to experiment this on a site other than face first , wait 4 to 6 weeks to see results before starting with face!