Neha Patel Sitole, MD, FACS

Botox and Restylane are frequently used together for very deep lines because they address the lines in two very different ways.  Botox relaxes the muscles that actually cause the line, and Restylane fills in the line.  Using Botox even if the line is filled helps keep the Restylane in place longer because Botox relaxes the muscles around it. 

What you are describing regarding the eye pain actually sounds like a eye surface problem like dry eyes.  Intermittent, sharp pain is typical of dry eyes.  It doesn't sound like anything that is vision threatening.  Usually botox injections in the forehead won't lead to dry eyes but sometimes after receiving botox injections, people become more aware of all symptoms around the eyes.  You should try over the counter artificial tears and it will probably resolve soon. 

Both Botox and Juvederm are placed below the surface of the skin, so skin care products can be used immediately after either injection.  The use of retinol with Botox and Juvederm is an effective way to target wrinkles from all the mechanisms of actions.