Good choice for deeper lines; long lasting. Updated on 23 Jan 2011: Selected Radiesse for nasolabial folds; have been using since 2006. Like any filler, appropriate material selection, and injector skill and experience, are the most important factors. Have had little downtime, minimal-to-moderate pain depending upon area of injection. Well worth the pain and expense for the results I've obtained. Updated on 12 Feb 2011: