Botox Cosmetic , Xeomin Cosmetic and Dysport are the 3 forms of Botulinum treatment available in Canada. They work to reduce dynamic wrinkles (meaning wrinkles that come with facial expression, such as the frown lines). For the frown, botulinum treatment is by far the best treatment for the dynamic aspect of the wrinkles. Keep in mind that any wrinkles that are there at rest will not go away with botulinum treatment, but often will improve. Fillers are great for volumizing the face, especially the cheeks, and lower face. Fillers in the glabella (frown lines) are associated with significant risks and are not the ideal option.