Dysport vs. Botox Injection- which lasts longer, costs less, works best

SarahM81 on 1 Mar 2012 at 10:00am

Botox vs. Reloxin

When Dysport was awaiting FDA approval (as a drug named "Reloxin"), there was much speculation about how it would compete with Botox in the market of injectables aimed at smoothing fine lines and wrinkles. The debate spanned from which product lasts longer to which product works faster and costs less.

While early studies comparing the two drugs could not conclusively answer these questions, time and experience have weighed in. 

When posed with the question- Dysport vs. Botox, what’s the difference?, doctors on RealSelf have some helpful information to share:

“Reloxin (Dysport) has less of a protein load than Botox. Clinically this means that Reloxin will result in the formation of fewer antibodies against it. Antibodies are what our bodies use to detect and destroy foreign proteins aka antigens (the injected medications). Hence the assumption is that with fewer antibodies being formed the clinical effects of Reloxin should last longer than those of Botox. That being said, some clinical trials indicate that Botox has longer lasting results.”Dr. Kamran Jafri


"The simple answer is they last the same if a bioequivalent  number of units are given .That being said, there are variables that would make one last longer or shorter, or would have them give a different effect. Such variables include: the dilution used (how many cc per vial) for each product and how many units used total." - Dr. Robert S. Bader

“Reloxin consists of the same basic ingredient as Botox which is Botlulinum Toxin A. This would be similar to asking what is the basic difference between Bayer Aspirin, Bufferin, Excedrin, Anacin, etc.? The answer is that they are all basically the same: Aspirin. In a recent study, Reloxin was shown to last of equal duration during multiple injections. However, in another, it was shown to spread farther than Botox when injected. This is both an advantage and disadvantage. In large muscles such as the forehead, you want the toxin to spread whereas in small muscles you do not want it to spread because it could affect neighboring muscles unfavorably.” – Dr. Otto Joseph Placik

In terms of Worth It Ratings today, RealSelf users score Botox at 65% and Dysport at 52%. Doctors across the board say one can be better than the other, but it depends on the patients. As always, it's best to consult with your doctor to determine which is best suited to match your desired results.