Deep Vein Clots - Inherited Conditions


Inherited conditions can lead to a genetic predisposition to develop venous thrombotic events (deep vein clots):

  • Factor V Leiden mutation (most common)
  • Activated protein C mutations
  • Antithrombin mutations
  • Protein C mutations
  • Protein S mutations
  • Elevated factor VIII levels
  • Prothrombin gene mutations
  • Dysfibrinogenemia

These conditions are frequently the cause of clot formation in young individuals (< 45 years) and may contribute to deep vein clots at any age.

To learn more about these conditions, or if you have developed a deep vein clot at an early age - or have had recurrent deep vein clots (more than 1), consult your doctor to get evaluated for these inherited conditions using a simple blood test.


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Article by
Buffalo Phlebologist