I started getting Restylane in 2004 for nasolabial folds at 39. We used any extra Restylane in my lips, which already had a great shape but I have a small mouth, so it helped it appear slightly bigger and the entire affect was amazing. Natual looking, no duck-bill overdone lips that look ridiculous and conspicuous. I'm 43 and most people think I'm in my 20's - that is best result I can ask for.
I had to go back every three months for a "refill" varying from 1/2 to 1 full syringe, for the first two years, then it was less and less frequently. Now it's just twice a year and it looks great.
The friends and family I've told about it can't believe I use anything because you absolutely cannot tell if you have a good DOCTOR (not office staff) putting it in! My doctor injects it and then very forcefully manipulates the Restylane in both the nasolabial folds and my lips - the results are beautiful and I can go out in public within an hour, with maximum benefit being about a month after lasting for several months. It's a great investment! :)