I'm slim. And had only a MINOR reaction--thank heavens. Took 3 months for one side of "puppet mouth lines" not to look like a swollen lump. Believe me I was frightened the first 3 weeks when it never improved. Please note others here have had a reaction to this "no allergy " product! Now 6 months later I see still these lumps- that seem very obvious in certain light. NOT worth it at all. And now I know why Michael Jackson looks so odd.