At 64 my hands were looking 74+ with thin, wrinkled, old looking hands. The skin would break easy, with a small nick causing bleeding. I used Retinin A cream every night, a small amount. In 4 months my hands definitly looked better, skin thicker, less small wrinkles and less lose skin. If you pinch the skin on the back of your hand and watch how long it takes to go back you can get an idea of how thin it is. Definite improvement and very satasified. My hands looked better for over a year without the cream. Now I have started using it again. I use a very small anount before bed. No bad reactions. It does take months, but works.
I'm in Thailand, I got it over the counter, 10 gm, 0.05% for $4. Brand was Johnson & Johnson, made in Thailand.