The pain was very mild with both Perlane and the Juvederm, but with the Juverderm I didn't use a dental block at all and the swelling was much less than when I did use a dental block. I had minimal bruising which lasted about 6 days (with both fillers), but unless I pulled my lip down, you couldn't tell. Out of both dermal fillers, Juvederm was BY FAR the best. Its been 6 months now and they still look like they did the first week!
What I noticed with the first injection (with the Perlane) is that using a menthol chapstick made them go down very much, so do not use a menthol chapstick (its an anti-inflammatory)!! I also take a Hyaluronic Acid vitamin (good for joints/bones anyway),available at any WalMart/Meijers/Health Foods Store, and it helped out a lot the second time with my lips keeping their plump shape.
I would recommend Juvederm over Perlane, but its all up to what you want and what is the right thing to use for you. I did notice that the Juvederm was thicker and where it was injected (wet/dry line for volume) it plumped out more than Perlane did. I would just say that to help keep them lasting longer is to NOT use any menthol chapstick and to take Hyaluronic Acid vitamin. I LOVE my lips and will do the Juvederm again (if needed) any day! Thank you to my doctor and to Juvederm Ultra Plus for giving me the plump pout I wanted!