I lost over 60lbs and lost the size of my breast from a D cup to an A. My self-esteem suffered when I looked at myself and found it difficult to be myself completely with my boyfriend.
Being in my prime this was a decision not difficult to make. I love it and would do it again if I had to. There are no downsides to doing plastic surgery as long as you don't try to fill an inner void by fixing the outside.