I've been using Latisse for over a year. I LOVE it! I had a Facelift 3 years ago and more people have asked about my eyelashes than my Facelift!
I use it every morning before I put on my make-up.
(I'm a face-down-in-the-pillow sleeper and feared I would leave most of the product on my pillow using it as directed).
I wipe a Q-tip along my eyelid to remove any anti-aging product(sigh). I put ONE drop in the Latisse bottlecap and dip a 'dedicated' eyeliner brush into the cap. One drop for both eyelids doubles how long a bottle will last making the cost waaay easier to rationalize. I clean the brush and cap almost everyday and haven't had any issues.
I highly reccommend this product. It's made such a huge difference in my lashes, I've been accused of wearing false eyelashes... Sweet.