Ironically, the best treatment for noticeable nasolabial folds (NLF) involves treating the areas around the NLF. Sculptra's only indication is for treating NLFs, and again ironically many of the world's top Sculptra injectors do not inject the fold itself, but the areas adjacent to the folds. By replacing the volume in the face in the cheeks and maxilla, NLFs are lessened in a natural manner.
Other injectable fillers such as Juvederm, Restylane, and Radiesse, as well as fat transfer can be used as well. It is much more important to choose your injecting physician most carefully than what product is used. Good luck and be well.