Will These Sculptra Lumps Be Permanent?

Jenny,
I am sorry to hear that you have had such an unfortunate response to your treatment. Lumps/bumps do occur in around 6% of Sculptra treatments. The overwhelming majority of these bumps are not visible, but can be felt.
The occurence is extremely technique dependent and "technique" includes:

The preparation of the Sculptra material
The actual injections
The aftercare

In the United States, the manufacturer, Sanofi-Aventis, Dermik, requires practitioners to undergo formal training on the use of Sculptra before they can order the product. In addition, its use is limited to plastic surgeons, dermatologists and certain otolaryngologists.
Your lumps will resorb (disappear) over time. You may be able to hasten the process with massage. Your risk of lumps with future treatments remains 6%. Make sure that future injectors are up to date on the latest "techniques." Good luck!

The good thing about most injectable products is that they are not permanent, so most problems that occur will resolve on their own over time. This is true for Sculptra. Nodule or granuloma formation with Sculptra is possible, but the first thing to try for any nodularity after injectable treatments, including Sculptra, is some gentle massage in an attempt to break up and disperse the product.
It is difficult to say whether a patient that has developed nodules or irregularities after Sculptra would be prone to developing further nodules. I do not typically place Sculptra near the mouth due to risk of irregularities or nodule formation, and instead limit my use of Sculptra to the deeper facial soft tissues such as those in the cheeks or temples.
Be sure to always discuss any post-injection concerns with your injector, and I always recommend seeing an expert physician injector.
All the best,

Thank you for
your question. Sculptra is long lasting but not permanent filler. This means
that your bumps will not be permanent. The bumps you are experiencing should
resolve once your filler wears off in 9 months. It is unlikely for this to
happen again. However, I would seek out a new expert injector for the future.
Best of Luck!