What's the Best Anti-wrinkle Cream?

What is the best anti wrinkle cream for sale? Wrinkles are around my eyes, forehead, and some lip lines too!

Doctor Answers (3)

Sunscreen is the best anti-wrinkle cream


No wrinkle cream works better than preventing wrinkles in the first place with a good broad-spectrum (UVA and UVB blocking) sunscreen.

Beverly Hills Oculoplastic Surgeon
5.0 out of 5 stars 32 reviews

Best wrinkle creams contain retinol


If you already have wrinkles, the best cream to reduce them is a cream containing retinol or retinoic acid. Initially using these creams will cause some mild peeling and irritation but typically the skin adjust to this and the dryness should only last a couple of weeks.

If you do not yet have any wrinkles and want to prevent them, the best cream to use is a sunblock with an SPF of 30 or higher, that contains zinc oxide. If it also contains avobenzone or mexoryl that is even better.

Jordana S. Gilman, MD
Atlanta Dermatologic Surgeon
5.0 out of 5 stars 2 reviews

Ultra Violet Light causes wrinkles and the best treatment is prevention.


The best anti-wrinkle cream is a good sunscreen that protects the skin against ultra violet light. The best sunscreens contain either zinc oxide or a combination of chemicals that include Mexoryl, and/or stabilized Avobenzone. To be truly effective, it has to be applied every day and in sufficient quantity to all sun exposed skin.

Robert Swanson, MD - RETIRED
Bay Area General Surgeon

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These answers are for educational purposes and should not be relied upon as a substitute for medical advice you may receive from your physician. If you have a medical emergency, please call 911. These answers do not constitute or initiate a patient/doctor relationship.