What is the Treatment for an Injection Granuloma?

An injection granuloma occurs when a medication is inadvertently injected into the fat rather than the muscle. This causes fat necrosis (fat death), scar formation, and sometimes calcium deposits. If the patient can not recall receiving an injection, these can feel like a soft tissue mass and occasionally lead to an erroneous diagnosis of sarcoma. Even under the microscope, this can be a tricky diagnosis. I remember as a pathology resident, this can pose a very difficult call in... more

An injection granuloma is the body's reaction for a retained foreign body or substance. It can resolve with a simple incision and drainage. If it does not -- you may need to have it excised and repaired properly.