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What is a Granuloma and What Causes It?

asked 3 years ago by anon
Latest answer by Chris Thiagarajah, MD
Question viewed 15,999 times
Tags: granuloma

What is a granuloma and can they be a side effect caused by dermal filler injections?

9 answers to What is a Granuloma and What Causes It?

+3

Granulomas from fillers

Granulomas are your body's reaction to foreign substance. They can occur when there is a foreign substance such as filler but can also occur when there is an incision or break in the skin and there is healing by the body...a pyogenic granuloma. Sometimes patients can have immune system diseases such as sarcoidosis which cause the body to create granulomas when there is not a foreign substance. Treatment includes massage, steroid injection, topical steroids and excision. For autoimmune cau more
Chris Thiagarajah, MD

Washington DC Oculoplastic Surgeon
+2

Granuloma Formation With Injectables

Thanks for your question - A granuloma is your body's immune response to a foreign body. There are substances that are more likely to cause granuloma formation and substances that are less likely to form granulomas. Most modern injectables (especially the HA injectables) typically do not form granulomas as they are minimally stimulating to your immune system. It is not impossible though. Discuss the lumps with your injector. They will likely recommend observation and time. The lumps will... more
Steven H. Williams, MD

San Francisco Plastic Surgeon
+2

Granulomas can occur after injections

Tara, Granulomas can occur after injections. However, just because you have a "lump" it does not mean it is a granuloma. Lumps after injections can be caused by localized palpable product, hematomas, swelling and granulomas. The first three occur early since they are due to the product or the procedure. The granulomas occur later - days to weeks - since they are due to an inflammatory reaction around the the product or nidus of infection. Clinic exam may help... more
David Shafer, MD

New York Plastic Surgeon
+1

Granuloma

Granulomas are a specific inflammatory reaction that is seen in soft tissue as a response to foreign bodies. The popularity of Juvederm and Restylane came about as a result of their high safety profiles and hence, their low rates of granuloma formation. Granulomas can occur, nonetheless, from any foreign body and require either surgical excision or TAC injection.
Raffy Karamanoukian, MD

Los Angeles Plastic Surgeon
+1

Yes, a granuloma may result from an injection

A granuloma is a mass or nodule (a lump or bump) usually associated with an infectious (bacterial or fungal for example) process that produces inflamation (swelling, redness and pain). A granuloma may resmble a foreign body reaction as with a splinter or, more to the point, from an injection of a substance, such as with dermal fillers used for cosmetic purposes to improve facial lines and enhance contour. True granulomas with any filler are quite rare. More commonly, too much... more
David J. Levens, MD

Coral Springs Plastic Surgeon
+1

A granuloma is a nodular form of tissue inflammation.

Granulomas can often form in response to biological, chemical or physical irritants including trauma. Granulomas do have characteristic pathologic findings when the tissue is examined under the microscope. As Ms. Imbesi indicated, granulomas should be distinguished from nodules that simply represent a collection of injected material. Certainly granulomas can form as an unwanted effect of dermal fillers. Generally speaking, the more "foreign" the injected material, the less... more
Bryan K. Chen, MD

San Diego Dermatologist
+1

Granuloma and dermal fillers

A granuloma is the bodies development of inflammed scar tissue around a foreign body. Yes, you can get them from injectable products.  They are less ikely to happen with absorbable products.
Steven Wallach, MD

Manhattan Plastic Surgeon
+1

Tissue reaction to a foreign substance

A granuloma is an inflammation of the tissues due to several causes. Injection of dermal fillers could cause a tissue reaction ,however this is extremely rare. It is important to see these lesions to make sure that this is not a nodule induced by superficial injection of the dermal filler or injecting a large volume in one spot.
Hisham Seify, MD, PhD

Los Angeles Plastic Surgeon
+1

A granuloma is a immune reaction. It is unlikely to be cause by fillers.

A granuloma is a immune reaction to either a foreign body or sometimes to some minor trauma.  It is very unlikely that the popular dermal fillers (Restylane, Perlane, or Juvaderm) would cause a granuloma.
Sean Wright, MD

Philadelphia Plastic Surgeon

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