Hi Z in Pakistan,
Yes, you can lift up the corners of your mouth without using any fillers.....SMILE!
Once you are tired of smiling, you can have a few strategically placed units of Botox, Dysport, or Xeomin into your depressor anguli oris muscles (the muscle that pulls the corner of our mouths down). Though you wish to elevate the corners of the mouth without fillers, we can very successfully elevate the corners with injectable fillers. Combination treatment is most effective.
These techniques are advanced methods, so be sure to choose your skilled and experienced injecting physician most carefully.
Good luck and be well.